Alpha-adrenergic stimulation of corticotropin secretion by a specific central mechanism in man.

In a double-blind study in normal subjects, methoxamine, a highly selective agonist at alpha-1-adrenoceptors, significantly increased circulating ACTH and cortisol. The stimulant effect of methoxamine on cortisol secretion was dose dependent in the range 3.5-7 micrograms/kg/min, was abolished by con...

Полное описание

Библиографические подробности
Главные авторы: Al-Damluji, S, Perry, L, Tomlin, S, Bouloux, P, Grossman, A, Rees, L, Besser, G
Формат: Journal article
Язык:English
Опубликовано: 1987