Identification of a transitional fibroblast functional phenotype in very early rheumatoid arthritis

Identification of a transitional fibroblast functional phenotype in very early rheumatoid arthritis

<p><strong>Objectives</strong> Synovial fibroblasts actively regulate the inflammatory infiltrate by communicating with neighbouring endothelial cells (EC). Surprisingly, little is known about how the development of rheumatoid arthritis (RA) alters these immunomodulatory properties...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Filer, A, Ward, L, Kemble, S, Davies, C, Munir, H, Rogers, R, Raza, K, Buckley, C, Nash, G, McGettrick, H
Format:	Journal article
Wydane:	BMJ Publishing Group 2017

Podobne zapisy

Leukocyte trafficking between stromal compartments: lessons from rheumatoid arthritis
od: Buckley, CD, i wsp.
Wydane: (2018)

The relationship between the presence of anti-cyclic citrullinated peptide antibodies and clinical phenotype in very early rheumatoid arthritis
od: Cader Mohammed Z, i wsp.
Wydane: (2010-08-01)

Fibroblasts as therapeutic targets in rheumatoid arthritis and cancer
od: Maria Juarez, i wsp.
Wydane: (2012-02-01)

What is the role of fibroblasts in rheumatoid arthritis?
od: Buckley, C
Wydane: (2004)

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a proinflammatory phenotype in Rheumatoid Arthritis
od: Wang, Y, i wsp.
Wydane: (2021)

Distinct fibroblast subsets drive inflammation and damage in arthritis
od: Croft, AP, i wsp.
Wydane: (2019)

Endogenous Galectin-9 Suppresses Apoptosis in Human Rheumatoid Arthritis Synovial Fibroblasts
od: Pearson, MJ, i wsp.
Wydane: (2018)

A proinflammatory response is mediated by synovial fibroblast and natural killer cell interaction in rheumatoid arthritis and spondyloarthritis
od: Chan, A, i wsp.
Wydane: (2008)

Mediation of the proinflammatory cytokine response in rheumatoid arthritis and spondylarthritis by interactions between fibroblast-like synoviocytes and natural killer cells.
od: Chan, A, i wsp.
Wydane: (2008)

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
od: Mizoguchi, F, i wsp.
Wydane: (2018)

Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
od: Xiangyu Ge, i wsp.
Wydane: (2021-08-01)

Detection of antibodies to citrullinated tenascin-C in patients with early synovitis is associated with the development of rheumatoid arthritis
od: Raza, K, i wsp.
Wydane: (2016)

Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
od: Fumitaka Mizoguchi, i wsp.
Wydane: (2018-02-01)

Genomic responses of mouse synovial fibroblasts during tumor necrosis factor-driven arthritogenesis greatly mimic those in human rheumatoid arthritis
od: Ntougkos, E, i wsp.
Wydane: (2017)

Response to: 'Potential roles for tenascin in (very) early diagnosis and treatment of rheumatoid arthritis' by Cutolo et al.
od: Aungier, S, i wsp.
Wydane: (2019)

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
od: Montero-Melendez, T, i wsp.
Wydane: (2020)

Vitamin D and early rheumatoid arthritis
od: Stephanie R. Harrison, i wsp.
Wydane: (2020-07-01)

The role of ultrasound-defined tenosynovitis and synovitis in the prediction of rheumatoid arthritis development
od: Sahbudin, I, i wsp.
Wydane: (2018)

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes
od: Alyssa Torres, i wsp.
Wydane: (2023-07-01)

Metabolic Checkpoints in Rheumatoid Arthritis
od: Valentina Pucino, i wsp.
Wydane: (2020-04-01)

PREDICTING RESPONSES TO ANTI-TNF alpha THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS USING METABOLOMIC ANALYSIS OF URINE
od: Kapoor, SR, i wsp.
Wydane: (2012)

Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis.
od: Kapoor, SR, i wsp.
Wydane: (2013)

Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis
od: Yilin Wang, i wsp.
Wydane: (2021-04-01)

Pre-symptomatic autoimmunity in rheumatoid arthritis: When does the disease start?
od: Tracy, A, i wsp.
Wydane: (2017)

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
od: Manuel J. Del Rey, i wsp.
Wydane: (2019-11-01)

Multiomics landscape of synovial fibroblasts in rheumatoid arthritis
od: Haruka Tsuchiya, i wsp.
Wydane: (2021-03-01)

Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
od: Trinidad Montero-Melendez, i wsp.
Wydane: (2020-02-01)

Notch signalling drives synovial fibroblast identity and arthritis pathology
od: Wei, K, i wsp.
Wydane: (2020)

Metabolic checkpoints in rheumatoid arthritis
od: Pucino, V, i wsp.
Wydane: (2020)

Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid Arthritis
od: Mohammad Javad Mousavi, i wsp.
Wydane: (2021-06-01)

Targeting Activated Synovial Fibroblasts in Rheumatoid Arthritis by Peficitinib
od: Magnus Diller, i wsp.
Wydane: (2019-03-01)

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
od: Marta F. Bustamante, i wsp.
Wydane: (2017-05-01)

Enhanced angiogenic function in response to fibroblasts from psoriatic arthritis synovium compared to rheumatoid arthritis
od: S. Fromm, i wsp.
Wydane: (2019-12-01)

Bimodal expansion of the lymphatic vessels is regulated by the sequential expression of IL-7 and lymphotoxin α1β2 in newly formed tertiary lymphoid structures
od: Nayar, S, i wsp.
Wydane: (2016)

Similar Transition Processes in Synovial Fibroblasts from Rheumatoid Arthritis and Osteoarthritis: A Single-Cell Study
od: Shaozhe Cai, i wsp.
Wydane: (2019-01-01)

Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis
od: Karouzakis, E, i wsp.
Wydane: (2018)

Detection and characterisation of bone destruction in murine rheumatoid arthritis using statistical shape models
od: Brown, J, i wsp.
Wydane: (2017)

Rheumatoid synovial fibroblasts differentiate into distinct subsets in the presence of cytokines and cartilage
od: Croft, AP, i wsp.
Wydane: (2016)

Citrullinated and malondialdehyde-acetaldehyde modified fibrinogen activates macrophages and promotes an aggressive synovial fibroblast phenotype in patients with rheumatoid arthritis
od: Nozima Aripova, i wsp.
Wydane: (2023-08-01)

Synovial tissue biopsy analysis: unlocking the hidden secrets to personalised medicine?
od: Helen Michelle McGettrick
Wydane: (2019-04-01)