ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.
Closure of ATP-regulated K(+) channels (K(ATP) channels) plays a central role in glucose-stimulated insulin secretion in beta cells. K(ATP) channels are also highly expressed in glucagon-producing alpha cells, where their function remains unresolved. Under hypoglycaemic conditions, K(ATP) channels a...
Հիմնական հեղինակներ: | Rorsman, P, Ramracheya, R, Rorsman, N, Zhang, Q |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2014
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Նմանատիպ նյութեր
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ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: Similar functions but reciprocal effects on secretion
: Rorsman, P, և այլն
Հրապարակվել է: (2014) -
Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterisation and involvement in insulin secretion
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Հրապարակվել է: (2007) -
Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.
: Braun, M, և այլն
Հրապարակվել է: (2008) -
Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets.
: Ramracheya, R, և այլն
Հրապարակվել է: (2010) -
l-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels
: Ida Marie Modvig, և այլն
Հրապարակվել է: (2024-06-01)