Sensitive and specific enzymatic assay for the determination of precursor forms of prostate-specific antigen after an activation step.

Sensitive and specific enzymatic assay for the determination of precursor forms of prostate-specific antigen after an activation step.

BACKGROUND: The proteome of the serine protease prostate-specific antigen (PSA) and its enzymatic properties have been clarified only recently. We have developed a specific and sensitive method for the measurement of active PSA and used it to measure proPSA in blood. METHODS: We used the synthetic...

Podrobná bibliografie
Hlavní autoři:	Niemelä, P, Lövgren, J, Karp, M, Lilja, H, Pettersson, K
Médium:	Journal article
Jazyk:	English
Vydáno:	2002

Podobné jednotky

Simultaneous quantification of human glandular kallikrein 2 and prostate-specific antigen mRNAs in peripheral blood from prostate cancer patients.
Autor: Ylikoski, A, a další
Vydáno: (2001)

Time-resolved fluorescence imaging for specific and quantitative immunodetection of human kallikrein 2 and prostate-specific antigen in prostatic tissue sections.
Autor: Siivola, P, a další
Vydáno: (2000)

Measurement of circulating forms of prostate-specific antigen in whole blood immediately after venipuncture: implications for point-of-care testing.
Autor: Piironen, T, a další
Vydáno: (2001)

Simultaneous quantification of prostate-specific antigen and human glandular kallikrein 2 mRNA in blood samples from patients with prostate cancer and benign disease.
Autor: Ylikoski, A, a další
Vydáno: (2002)

Intact free prostate-specific antigen and free and total human glandular kallikrein 2. Elimination of assay interference by enzymatic digestion of antibodies to F(ab')2 fragments.
Autor: Väisänen, V, a další
Vydáno: (2006)

Biology of prostate-specific antigen
Autor: Lilja, H
Vydáno: (2003)

Biology of prostate-specific antigen.
Autor: Lilja, H
Vydáno: (2003)

Immunoassay for the discrimination of free prostate-specific antigen (fPSA) forms with internal cleavages at Lys(₁₄₅) or Lys(₁₄₆) from fPSA without internal cleavages at Lys(₁₄₅) or Lys(₁₄₆).
Autor: Peltola, M, a další
Vydáno: (2011)

Association of free-prostate specific antigen subfractions and human glandular kallikrein 2 with volume of benign and malignant prostatic tissue.
Autor: Steuber, T, a další
Vydáno: (2005)

[Isoforms of free prostate-specific antigen]
Autor: Haese, A, a další
Vydáno: (2004)

Isoforms of free prostate-specific antigen
Autor: Haese, A, a další
Vydáno: (2004)

Enzymatic action of prostate-specific antigen (PSA or hK3): substrate specificity and regulation by Zn(2+), a tight-binding inhibitor.
Autor: Malm, J, a další
Vydáno: (2000)

Prostate-specific antigen and prostate cancer: prediction, detection and monitoring.
Autor: Lilja, H, a další
Vydáno: (2008)

Clinical value of human glandular kallikrein 2 and free and total prostate-specific antigen in serum from a population of men with prostate-specific antigen levels 3.0 ng/mL or greater.
Autor: Becker, C, a další
Vydáno: (2000)

Testing in serum for human glandular kallikrein 2, and free and total prostate specific antigen in biannual screening for prostate cancer
Autor: Becker, C, a další
Vydáno: (2003)

Testing in serum for human glandular kallikrein 2, and free and total prostate specific antigen in biannual screening for prostate cancer.
Autor: Becker, C, a další
Vydáno: (2003)

Early prostate-specific antigen changes and the diagnosis and prognosis of prostate cancer.
Autor: Botchorishvili, G, a další
Vydáno: (2009)

Comparison of free and total forms of serum human kallikrein 2 and prostate-specific antigen for prediction of locally advanced and recurrent prostate cancer.
Autor: Steuber, T, a další
Vydáno: (2007)

A Specific and Sensitive Enzymatic Assay for the Quantitation of L-Proline
Autor: Giuseppe Forlani, a další
Vydáno: (2020-10-01)

Prostate-specific antigen and related isoforms in the diagnosis and management of prostate cancer.
Autor: Haese, A, a další
Vydáno: (2004)

Molecular insights into substrate specificity of prostate specific antigen through structural modeling.
Autor: Singh, P, a další
Vydáno: (2009)

Evaluation of molecular forms of prostate-specific antigen and human kallikrein 2 in predicting biochemical failure after radical prostatectomy.
Autor: Wenske, S, a další
Vydáno: (2009)

Taxon-specific evolution of glandular kallikrein genes and identification of a progenitor of prostate-specific antigen.
Autor: Olsson, A, a další
Vydáno: (2004)

Anti-thrombin is expressed in the benign prostatic epithelium and in prostate cancer and is capable of forming complexes with prostate-specific antigen and human glandular kallikrein 2.
Autor: Cao, Y, a další
Vydáno: (2002)

An empirical evaluation of guidelines on prostate-specific antigen velocity in prostate cancer detection.
Autor: Vickers, A, a další
Vydáno: (2011)

The role of prostate-specific antigen in the prediction of hormone-sensitive prostate cancer
Autor: A. A. Gritskevich, a další
Vydáno: (2015-12-01)

Discrimination of benign from malignant prostatic disease by selective measurements of single chain, intact free prostate specific antigen.
Autor: Steuber, T, a další
Vydáno: (2002)

Targeting free prostate-specific antigen for in vivo imaging of prostate cancer using a monoclonal antibody specific for unique epitopes accessible on free prostate-specific antigen alone.
Autor: Evans-Axelsson, S, a další
Vydáno: (2012)

Discrimination of prostate cancer from benign disease by plasma measurement of intact, free prostate-specific antigen lacking an internal cleavage site at Lys145-Lys146.
Autor: Nurmikko, P, a další
Vydáno: (2001)

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer.
Autor: Denmeade, SR, a další
Vydáno: (2003)

Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies
Autor: Nouira Yassin, a další
Vydáno: (2010-12-01)

Dual-label detection of amplified products in quantitative RT-PCR assay using lanthanide-labeled probes.
Autor: Ylikoski, A, a další
Vydáno: (2001)

Development and Validation of a Highly Informative Immuno-Enzymatic Analysis for the Determination of Free Prostat-Specific Antigen
Autor: Anatolii Komar, a další
Vydáno: (2019-12-01)

Systematic review of pretreatment prostate-specific antigen velocity and doubling time as predictors for prostate cancer.
Autor: Vickers, A, a další
Vydáno: (2009)

Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.
Autor: Ulmert, D, a další
Vydáno: (2012)

The performance characteristics of prostate-specific antigen and prostate-specific antigen density in Chinese men
Autor: Jeremy YC Teoh, a další
Vydáno: (2017-01-01)

Specificity and sensitivity of preoperative total serum prostate specific antigen in diagnosis most common histopathological change of prostate
Autor: Mijović Milica, a další
Vydáno: (2017-01-01)

Clinical significance of the LacdiNAc-glycosylated prostate-specific antigen assay for prostate cancer detection
Autor: T. Yoneyama, a další
Vydáno: (2020-07-01)

Inhibition of dendropoiesis by tumor derived and purified prostate specific antigen.
Autor: Aalamian, M, a další
Vydáno: (2003)

On the use of prostate-specific antigen for screening of prostate cancer in European Randomised Study for Screening of Prostate Cancer.
Autor: Bangma, C, a další
Vydáno: (2010)