Tumor-associated changes in intestinal epithelial cells cause local accumulation of KLRG1(+) GATA3(+) regulatory T cells in mice

CD4(+) Foxp3(+) regulatory T cells (Treg) include differentiated populations of effector Treg characterized by the expression of specific transcription factors. Tumors, including intestinal malignancies, often present with local accumulation of Treg that can prevent tumor clearance, but how tumor pr...

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Bibliographic Details
Main Authors: Meinicke, H, Bremser, A, Brack, M, Akeus, P, Pearson, C, Bullers, S, Hoffmeyer, K, Stemmler, M, Quiding-Järbrink, M, Izcue, A
Format: Journal article
Language:English
Published: John Wiley & Sons Ltd 2017