Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens.

No vaccine has yet proven effective against the blood-stages of Plasmodium falciparum, which cause the symptoms and severe manifestations of malaria. We recently found that PfRH5, a P. falciparum-specific protein expressed in merozoites, is efficiently targeted by broadly-neutralizing, vaccine-induc...

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Príomhchruthaitheoirí: Williams, A, Douglas, A, Miura, K, Illingworth, J, Choudhary, P, Murungi, L, Furze, J, Diouf, A, Miotto, O, Crosnier, C, Wright, G, Kwiatkowski, D, Fairhurst, R, Long, C, Draper, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Public Library of Science 2012