Comparison of the simulated response of three in silico human stem cell-derived cardiomyocytes models and in vitro data under 15 drug actions
Improvements in human stem cell-derived cardiomyocyte (hSC-CM) technology have promoted their use for drug testing and disease investigations. Several in silico hSC-CM models have been proposed to augment interpretation of experimental findings through simulations. This work aims to assess the respo...
المؤلفون الرئيسيون: | Paci, M, T Koivumäki, J, Lu, HR, Gallacher, DJ, Passini, E, Rodriguez, B |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Frontiers Media
2021
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مواد مشابهة
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Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions
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منشور في: (2021-03-01) -
Phenotypic variability in LQT3 human induced pluripotent stem cell-derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach
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A population of in silico models to face the variability of human induced pluripotent stem cell-derived cardiomyocytes: the hERG block case study
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In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes
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Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes
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