Comparison of the simulated response of three in silico human stem cell-derived cardiomyocytes models and in vitro data under 15 drug actions
Improvements in human stem cell-derived cardiomyocyte (hSC-CM) technology have promoted their use for drug testing and disease investigations. Several in silico hSC-CM models have been proposed to augment interpretation of experimental findings through simulations. This work aims to assess the respo...
Main Authors: | Paci, M, T Koivumäki, J, Lu, HR, Gallacher, DJ, Passini, E, Rodriguez, B |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2021
|
Similar Items
-
Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions
by: Michelangelo Paci, et al.
Published: (2021-03-01) -
Phenotypic variability in LQT3 human induced pluripotent stem cell-derived cardiomyocytes and their response to antiarrhythmic pharmacologic therapy: An in silico approach
by: Paci, M, et al.
Published: (2017) -
A population of in silico models to face the variability of human induced pluripotent stem cell-derived cardiomyocytes: the hERG block case study
by: Paci, M, et al.
Published: (2017) -
In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes
by: Mohamadamin Forouzandehmehr, et al.
Published: (2024-04-01) -
Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes
by: Paci Michelangelo, et al.
Published: (2012-08-01)