Comparison of the simulated response of three in silico human stem cell-derived cardiomyocytes models and in vitro data under 15 drug actions

Improvements in human stem cell-derived cardiomyocyte (hSC-CM) technology have promoted their use for drug testing and disease investigations. Several in silico hSC-CM models have been proposed to augment interpretation of experimental findings through simulations. This work aims to assess the respo...

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Hlavní autoři: Paci, M, T Koivumäki, J, Lu, HR, Gallacher, DJ, Passini, E, Rodriguez, B
Médium: Journal article
Jazyk:English
Vydáno: Frontiers Media 2021