Expression of tak1 and tram induces synergistic pro-inflammatory signalling and adjuvants DNA vaccines.

Expression of tak1 and tram induces synergistic pro-inflammatory signalling and adjuvants DNA vaccines.

Improving vaccine immunogenicity remains a major challenge in the fight against developing country diseases like malaria and AIDS. We describe a novel strategy to identify new DNA vaccine adjuvants. We have screened components of the Toll-like receptor signalling pathways for their ability to activa...

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Bibliographic Details
Main Authors: Larsen, K, Spencer, A, Goodman, A, Gilchrist, A, Furze, J, Rollier, C, Kiss-Toth, E, Gilbert, S, Bregu, M, Soilleux, E, Hill, A, Wyllie, D
Format: Journal article
Language:English
Published: 2009

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