Towards a structural understanding of drug and peptide transport within the proton-dependent oligopeptide transporter (POT) family.

Towards a structural understanding of drug and peptide transport within the proton-dependent oligopeptide transporter (POT) family.

One of the principal aims of modern drug design is the targeted delivery of drugs within the body, such as to the central nervous system, combined with their exclusion from the liver and kidneys, which break down foreign molecules and subsequently eliminate them. Many of the commonly prescribed drug...

Bibliografski detalji
Glavni autor:	Newstead, S
Format:	Journal article
Jezik:	English
Izdano:	2011

Slični predmeti

Towards a Structural Understanding of Alternating Access within the Proton Dependent Oligopeptide Transporter (POT) Family
od: Newstead, S
Izdano: (2012)

Recent advances in understanding proton coupled peptide transport via the POT family
od: Newstead, S
Izdano: (2016)

Symmetry and structure in the POT family of proton coupled peptide transporters
od: Newstead, S
Izdano: (2017)

Alternating access mechanism in the POT family of oligopeptide transporters.
od: Solcan, N, i dr.
Izdano: (2012)

Alternating access mechanism in the POT family of oligopeptide transporters
od: Solcan, N, i dr.
Izdano: (2012)

Proton movement and coupling in the POT family of peptide transporters
od: Parker, J, i dr.
Izdano: (2018)

Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter
od: Newstead, S, i dr.
Izdano: (2016)

Energetics of substrate transport in proton-dependent oligopeptide transporters
od: Balaji Selvam, i dr.
Izdano: (2024-12-01)

Structural insights into substrate recognition in proton-dependent oligopeptide transporters
od: Quistgaard, Esben M., i dr.
Izdano: (2013)

Improving oral drug delivery: computational studies of proton dependent oligopeptide transporters
od: Samsudin, M
Izdano: (2015)

Biochemical and biophysical studies of the prokaryotic proton dependent oligopeptide transporters
od: Solcan, N
Izdano: (2013)

Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.
od: Doki, S, i dr.
Izdano: (2013)

Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters
od: Minhas, G, i dr.
Izdano: (2019)

Structural basis for proton coupled amino acid and peptide transport
od: Newstead, S
Izdano: (2017)

Thermodynamic evidence for a dual transport mechanism in a POT peptide transporter
od: Joanne L Parker, i dr.
Izdano: (2014-12-01)

Molecular Dynamics Simulations Reveal the Proton:Peptide Coupling Mechanism in the Bacterial Proton-Coupled Oligopeptide Transporter YbgH
od: Nanda G. Aduri, i dr.
Izdano: (2019-01-01)

The mechanism of mammalian proton-coupled peptide transporters
od: Simon M Lichtinger, i dr.
Izdano: (2024-07-01)

Analyses of the oligopeptide transporter gene family in poplar and grape
od: Yang Yongping, i dr.
Izdano: (2011-09-01)

Exploring conformational transitions and free-energy profiles of proton-coupled oligopeptide transporters
od: Batista, MRB, i dr.
Izdano: (2019)

Molecular Insights to the Structure-Interaction Relationships of Human Proton-Coupled Oligopeptide Transporters (PepTs)
od: Yining Luo, i dr.
Izdano: (2023-10-01)

Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle.
od: Ashley M Groshong, i dr.
Izdano: (2021-01-01)

Proton-control of transitions in an amino-acid transporter
od: Wu, Z, i dr.
Izdano: (2019)

Proton-control of transitions in an amino-acid transporter
od: Wu, Z, i dr.
Izdano: (2019)

Molecular and structural basis of oligopeptide recognition by the Ami transporter system in pneumococci.
od: Martín Alcorlo, i dr.
Izdano: (2024-06-01)

Electrophysiological analysis of the epithelial H+/oligopeptide transporter, PepT1
od: Beattie, L, i dr.
Izdano: (2001)

Structural basis for amino acid transport by the CAT family of SLC7 transporters
od: Jungnickel, K, i dr.
Izdano: (2018)

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2.
od: Newstead, S, i dr.
Izdano: (2011)

Crystal structure of a prokaryotic homologue of the mammalian oligopeptide-proton symporters, PepT1 and PepT2
od: Newstead, S, i dr.
Izdano: (2011)

Oligopeptides as Biomarkers of Cyanobacterial Subpopulations. Toward an Understanding of Their Biological Role
od: Ramsy Agha, i dr.
Izdano: (2014-06-01)

Structural basis for proton coupled cystine transport by cystinosin
od: Löbel, M, i dr.
Izdano: (2022)

Structural basis for proton coupled cystine transport by cystinosin
od: Mark Löbel, i dr.
Izdano: (2022-08-01)

Two mechanisms of membrane digestion: enzymatic-transport ensemble exists for oligopeptides as well
od: S. T. Metelsky, i dr.
Izdano: (2011-05-01)

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages.
od: Arunava Dasgupta, i dr.
Izdano: (2010-01-01)

Molecular mechanisms of drug transport through peptide transporters
od: Lichtinger, SM
Izdano: (2024)

Genome-wide analysis indicates diverse physiological roles of the turnip (Brassica rapa var. rapa) oligopeptide transporters gene family
od: Yanan Pu, i dr.
Izdano: (2018-04-01)

The Knock-Down of the Chloroquine Resistance Transporter PfCRT Is Linked to Oligopeptide Handling in Plasmodium falciparum
od: Cecilia P. Sanchez, i dr.
Izdano: (2022-08-01)

Structural insights into polyamine spermidine uptake by the ABC transporter PotD-PotABC
od: Qiao, Zhu, i dr.
Izdano: (2024)

The Oligopeptide Permease Opp Mediates Illicit Transport of the Bacterial P-site Decoding Inhibitor GE81112
od: Alessandro Maio, i dr.
Izdano: (2016-05-01)

Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters
od: Cheng-Hsun Ho, i dr.
Izdano: (2014-03-01)

TcOPT3, a member of oligopeptide transporters from the hyperaccumulator Thlaspi caerulescens, is a novel Fe/Zn/Cd/Cu transporter.
od: Yi Ting Hu, i dr.
Izdano: (2012-01-01)