Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice.
Transgenic mice have been constructed expressing high (CD45RABC) and low (CD45R0) molecular weight CD45 isoforms on a CD45-/- background. Phenotypic analysis and in vivo challenge of these mice with influenza and lymphocytic choriomeningitis viruses shows that T cell differentiation and peripheral T...
Main Authors: | Tchilian, E, Dawes, R, Hyland, L, Montoya, M, Le Bon, A, Borrow, P, Hou, S, Tough, D, Beverley, P |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2004
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