Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice.

Altered CD45 isoform expression affects lymphocyte function in CD45 Tg mice.

Transgenic mice have been constructed expressing high (CD45RABC) and low (CD45R0) molecular weight CD45 isoforms on a CD45-/- background. Phenotypic analysis and in vivo challenge of these mice with influenza and lymphocytic choriomeningitis viruses shows that T cell differentiation and peripheral T...

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Bibliographic Details
Main Authors:	Tchilian, E, Dawes, R, Hyland, L, Montoya, M, Le Bon, A, Borrow, P, Hou, S, Tough, D, Beverley, P
Format:	Journal article
Language:	English
Published:	2004

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