2'-Alkynyl spin-labelling is a minimally perturbing tool for DNA structural analysis

The determination of distances between specific points in nucleic acids is essential to understanding their behaviour at the molecular level. The ability to measure distances of 2-10 nm is particularly important: deformations arising from protein binding commonly fall within this range, but the reli...

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Detalhes bibliográficos
Principais autores: Hardwick, JS, Haugland, MM, El-Sagheer, AH, Ptchelkine, D, Beierlein, FR, Lane, AN, Brown, T, Lovett, JE, Anderson, EA
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2020