Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2

Control of epithelial cell migration and invasion by the IKKβ- and CK1α-mediated degradation of RAPGEF2

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Epithelial cell migration is crucial for the development and regeneration of epithelial tissues. Aberrant regulation of epithelial cell migration has a major role in pathological processes such as the development of cancer metastasis and tissue fibrosis. Here, we report that in response to factors t...

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Bibliographic Details
Main Authors: Magliozzi, R, Low, T, Weijts, B, Cheng, T, Spanjaard, E, Mohammed, S, vanVeen, A, Ovaa, H, deRooij, J, Zwartkruis, F, Bos, J, deBruin, A, Heck, A, Guardavaccaro, D
Format: Journal article
Language:English
Published: 2013

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