Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).

The human concentrative nucleoside transporter 2 (CNT2) plays an important role in the absorption, disposition, and biological effects of endogenous nucleosides and nucleoside analog drugs. We identified genetic variation in the basal promoter region of CNT2 and characterized the function of the var...

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Bibliographic Details
Main Authors: Yee, S, Shima, J, Hesselson, S, Nguyen, L, De Val, S, Lafond, R, Kawamoto, M, Johns, S, Stryke, D, Kwok, P, Ferrin, T, Black, B, Gurwitz, D, Ahituv, N, Giacomini, K
Format: Journal article
Language:English
Published: 2009