Defining mechanisms of NOD2 receptor function in myeloid cells
<p>Pattern recognition receptors (PRRs) recognise foreign antigen to direct innate and adaptive immune responses against invading pathogens. Polymorphisms in the PRR NOD2 represent the strongest genetic risk factor for the inflammatory bowel disease Crohn’s, and thus this bacterial sensor i...
Main Author: | Chapman, TPE |
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Other Authors: | Simmons, A |
Format: | Thesis |
Published: |
2017
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