Strain variation in susceptibility to monoclonal antibody-induced transplantation tolerance.

BACKGROUND: We have reproducibly induced specific tolerance to multiple minor histocompatibility antigens with nondepleting anti-CD4 and -CD8 monoclonal antibodies. The tolerance induced is effective for the lifetime of the host. We have tested this therapy in a number of mouse strain combinations t...

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Bibliographic Details
Main Authors: Davies, J, Cobbold, S, Waldmann, H
Format: Journal article
Language:English
Published: 1997