A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

COVID-19 caused by SARS-CoV-2 has become a global pandemic requiring the development of interventions for the prevention or treatment to curtail mortality and morbidity. No vaccine to boost mucosal immunity, or as a therapeutic, has yet been developed to SARS-CoV-2. In this study, we discover and ch...

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Príomhchruthaitheoirí: Ejemel, M, Li, Q, Hou, S, Schiller, ZA, Tree, JA, Wallace, A, Amcheslavsky, A, Kurt Yilmaz, N, Buttigieg, KR, Elmore, MJ, Godwin, K, Coombes, N, Toomey, JR, Schneider, R, Ramchetty, AS, Close, BJ, Chen, D-Y, Conway, HL, Saeed, M, Ganesa, C, Carroll, MW, Cavacini, LA, Klempner, MS, Schiffer, CA, Wang, Y
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Springer Nature 2020