Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum.

Comparisons of immunoglobulin G (IgG) subclass responses to the major polymorphic region and to a conserved region of MSP-1 in three cohorts of African villagers exposed to Plasmodium falciparum revealed that responses to Block 2 are predominantly IgG3 whereas antibodies to MSP-1(19) are mainly IgG1...

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Bibliographic Details
Main Authors: Cavanagh, DR, Dobaño, C, Elhassan, I, Marsh, K, Elhassan, A, Hviid, L, Khalil, E, Theander, T, Arnot, D, McBride, J
Format: Journal article
Language:English
Published: 2001