A Stille cyclisation approach to (-)-periplanone-B: studies in alkene-selective ring-closing metathesis and an improved chromium(II)-mediated synthesis of (E)-alkenylstannanes from aldehydes
A synthesis of the dienone 7 via an efficient intramolecular Stille cross-coupling reaction, an improved chromium(n)mediated synthesis of (£)-alkenylstannanes from aldehydes using Bu3SnCHI2 in DMF, and a synthesis of the substituted (-)-dienone 25 via ring-closing alkene metathesis to give dihydropy...
| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
1999
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| Sammanfattning: | A synthesis of the dienone 7 via an efficient intramolecular Stille cross-coupling reaction, an improved chromium(n)mediated synthesis of (£)-alkenylstannanes from aldehydes using Bu3SnCHI2 in DMF, and a synthesis of the substituted (-)-dienone 25 via ring-closing alkene metathesis to give dihydropyran 22 are described. The synthesis of (-)-dienone 25 constitutes a formal synthesis of (-)-periplanone-B. © The Royal Society of Chemistry 1999. |
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