Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment

Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment

Hypoxia signaling influences tumor development through both cell-intrinsic and -extrinsic pathways. Inhibiting hypoxia-inducible factor (HIF) function has recently been approved as a cancer treatment strategy. Hence, it is important to understand how regulators of HIF may affect tumor growth under p...

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Main Authors:	Ma, J, Al Moussawi, K, Lou, H, Chan, HF, Wang, Y, Chadwick, J, Phetsouphanh, C, Slee, EA, Zhong, S, Leissing, TM, Roth, A, Qin, X, Chen, S, Yin, J, Ratnayaka, I, Hu, Y, Louphrasitthiphol, P, Taylor, L, Bettencourt, PJG, Muers, M, Greaves, DR, McShane, H, Goldin, R, Soilleux, EJ, Coleman, ML, Ratcliffe, PJ, Lu, X
Format:	Journal article
Language:	English
Published:	National Academy of Sciences 2024

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