Simultaneous determination of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA using online column-switching liquid chromatography/tandem mass spectrometry.

Simultaneous determination of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA using online column-switching liquid chromatography/tandem mass spectrometry.

Sensitive and reliable methods are required for the assessment of oxidative DNA damage, which can result from reactive oxygen species that are generated endogenously from cellular metabolism and inflammatory responses, or by exposure to exogenous agents. The development of a liquid chromatography/ta...

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Dettagli Bibliografici
Autori principali:	Singh, R, Teichert, F, Verschoyle, R, Kaur, B, Vives, M, Sharma, R, Steward, W, Gescher, A, Farmer, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	2009

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