Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford.
Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson's disease and related disorders. Here, we summarize our non-human primate and neuroimaging research of relevan...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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| _version_ | 1797090929577820160 |
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| author | Pereira, E Muthusamy, K De Pennington, N Joint, C Aziz, T |
| author_facet | Pereira, E Muthusamy, K De Pennington, N Joint, C Aziz, T |
| author_sort | Pereira, E |
| collection | OXFORD |
| description | Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson's disease and related disorders. Here, we summarize our non-human primate and neuroimaging research of relevance to our surgical targeting of the PPN. We also describe our clinical experience of PPN DBS with greatest motor improvements achieved by stimulation at low frequencies. |
| first_indexed | 2024-03-07T03:25:42Z |
| format | Journal article |
| id | oxford-uuid:b8f67980-5fdc-4301-953c-7ddf4028ffc0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:25:42Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:b8f67980-5fdc-4301-953c-7ddf4028ffc02022-03-27T04:59:37ZDeep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b8f67980-5fdc-4301-953c-7ddf4028ffc0EnglishSymplectic Elements at Oxford2008Pereira, EMuthusamy, KDe Pennington, NJoint, CAziz, TDeep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) is a novel neurosurgical therapy developed to address symptoms of gait freezing and postural instability in Parkinson's disease and related disorders. Here, we summarize our non-human primate and neuroimaging research of relevance to our surgical targeting of the PPN. We also describe our clinical experience of PPN DBS with greatest motor improvements achieved by stimulation at low frequencies. |
| spellingShingle | Pereira, E Muthusamy, K De Pennington, N Joint, C Aziz, T Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title | Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title_full | Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title_fullStr | Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title_full_unstemmed | Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title_short | Deep brain stimulation of the pedunculopontine nucleus in Parkinson's disease. Preliminary experience at Oxford. |
| title_sort | deep brain stimulation of the pedunculopontine nucleus in parkinson s disease preliminary experience at oxford |
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