5-Formylcytosine does not change the global structure of DNA

5-Formylcytosine does not change the global structure of DNA

The mechanism by which 5-formylcytosine (fC) is recognised by enzymes involved in epigenetic modification and reading of DNA is not known, and recently an unusual DNA structure (F-DNA) was proposed as the basis for enzyme recognition of clusters of fC. We used NMR and X-ray crystallography to compar...

Podrobná bibliografie
Hlavní autoři:	Hardwick, J, Ptchelkine, D, El-Sagheer, A, Tear, I, Singleton, D, Phillips, S, Lane, A, Brown, T
Médium:	Journal article
Vydáno:	Nature Publishing Group 2017

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