5-Formylcytosine does not change the global structure of DNA
The mechanism by which 5-formylcytosine (fC) is recognised by enzymes involved in epigenetic modification and reading of DNA is not known, and recently an unusual DNA structure (F-DNA) was proposed as the basis for enzyme recognition of clusters of fC. We used NMR and X-ray crystallography to compar...
| Main Authors: | , , , , , , , |
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| Formato: | Journal article |
| Publicado em: |
Nature Publishing Group
2017
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