Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae.
We show that, in the malaria vector Anopheles gambiae, expression of Cecropin 1 is regulated by REL2, an NF-kappaB-like transcription factor orthologous to Drosophila Relish. Through alternative splicing, REL2 produces a full-length (REL2-F) and a shorter (REL2-S) protein isoform lacking the inhibit...
Main Authors: | Meister, S, Kanzok, S, Zheng, X, Luna, C, Li, T, Hoa, N, Clayton, JR, White, K, Kafatos, F, Christophides, G, Zheng, L |
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Format: | Journal article |
Language: | English |
Published: |
2005
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