Role of adhesion molecules in activation signaling in T lymphocytes.

The T cell and antigen-presenting cell communicate to initiate an immune response through formation of an immunological synapse. This specialized cell-cell junction is compartmentalized into adhesion molecule and T cell receptor enriched regions or SMACs. Distinct signals seem to be generated in the...

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Bibliographic Details
Main Author: Dustin, M
Format: Journal article
Language:English
Published: 2001