The potential for Toll-like receptors to collaborate with other innate immune receptors.
Cells of the innate immune system express a large repertoire of germ-line encoded cell-surface glycoprotein receptors including Toll-like receptors (TLRs). TLRs recognize conserved motifs on microbes and induce inflammatory signals. Evidence suggests that individual members of the TLR family or othe...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
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2004
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author | Mukhopadhyay, S Herre, J Brown, G Gordon, S |
author_facet | Mukhopadhyay, S Herre, J Brown, G Gordon, S |
author_sort | Mukhopadhyay, S |
collection | OXFORD |
description | Cells of the innate immune system express a large repertoire of germ-line encoded cell-surface glycoprotein receptors including Toll-like receptors (TLRs). TLRs recognize conserved motifs on microbes and induce inflammatory signals. Evidence suggests that individual members of the TLR family or other non-TLR surface antigens either physically or functionally interact with each other and cumulative effects of these interactions instruct the nature and outcome of the immune response to a particular pathogen. |
first_indexed | 2024-03-07T03:26:10Z |
format | Journal article |
id | oxford-uuid:b91bb571-59a6-4b1e-8807-8ec7c88fa7c8 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T03:26:10Z |
publishDate | 2004 |
record_format | dspace |
spelling | oxford-uuid:b91bb571-59a6-4b1e-8807-8ec7c88fa7c82022-03-27T05:00:41ZThe potential for Toll-like receptors to collaborate with other innate immune receptors.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b91bb571-59a6-4b1e-8807-8ec7c88fa7c8EnglishSymplectic Elements at Oxford2004Mukhopadhyay, SHerre, JBrown, GGordon, SCells of the innate immune system express a large repertoire of germ-line encoded cell-surface glycoprotein receptors including Toll-like receptors (TLRs). TLRs recognize conserved motifs on microbes and induce inflammatory signals. Evidence suggests that individual members of the TLR family or other non-TLR surface antigens either physically or functionally interact with each other and cumulative effects of these interactions instruct the nature and outcome of the immune response to a particular pathogen. |
spellingShingle | Mukhopadhyay, S Herre, J Brown, G Gordon, S The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title | The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title_full | The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title_fullStr | The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title_full_unstemmed | The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title_short | The potential for Toll-like receptors to collaborate with other innate immune receptors. |
title_sort | potential for toll like receptors to collaborate with other innate immune receptors |
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