Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin.
The human neurological disease known as ataxia with oculomotor apraxia 1 is caused by mutations in the APTX gene that encodes Aprataxin (APTX) protein. APTX is a member of the histidine triad superfamily of nucleotide hydrolases and transferases but is distinct from other family members in that it a...
Main Authors: | Rass, U, Ahel, I, West, S |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Actions of aprataxin in multiple DNA repair pathways.
by: Rass, U, et al.
Published: (2007) -
Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease.
by: Tumbale, P, et al.
Published: (2011) -
Defective DNA repair and neurodegenerative disease.
by: Rass, U, et al.
Published: (2007) -
The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
by: Helena B. Madsen, et al.
Published: (2023-12-01) -
Molecular Insights into mRNA Polyadenylation and Deadenylation
by: Junjie Liu, et al.
Published: (2022-09-01)