Development of two processes for the synthesis of bridged azabicyclic systems: intermolecular radical addition-homoallylic rearrangements leading to 2-azanorborn-5-enes and neophyl-type radical rearrangements to 2-azabenzonorbornanes.
Radical thiol additions to 7-azanorbornadienes give 7-thio-substituted 2-azanorbornenes and Barton deoxygenations of 7-azabenzonorbornanols give 2-azabenzonorbornanes. The processes both involve novel nitrogen-directed radical rearrangements. The kinetics and mechanisms of the reactions are also dis...
मुख्य लेखकों: | Hodgson, D, Bebbington, M, Willis, P |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2003
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समान संसाधन
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2-azabenzonorbornanes from 7-azabenzonorbornanols by a nitrogen-directed neophyl-type radical rearrangement.
द्वारा: Hodgson, D, और अन्य
प्रकाशित: (2002) -
2-Azabicyclo[2.2.1]hept-5-enes from 7-azabicyclo[2.2.1]heptadienes by tandem intermolecular radical addition-homoallylic radical rearrangement
द्वारा: Hodgson, D, और अन्य
प्रकाशित: (2001) -
2-azabicyclo[2.2.1]-5-heptenes from 7-azabicyclo[2.2.1]heptadienes by tandem intermolecular radical addition - Homoallylic rearrangement.
द्वारा: Hodgson, D, और अन्य
प्रकाशित: (2001) -
Synthesis of azabicyclic systems using nitrogen-directed radical rearrangements.
द्वारा: Hodgson, D, और अन्य
प्रकाशित: (2007) -
Enantioselective access to isoquinuclidines by tropenone desymmetrization and homoallylic radical rearrangement: synthesis of (+)-ibogamine.
द्वारा: Hodgson, D, और अन्य
प्रकाशित: (2005)