Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.

Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.

AIMS/HYPOTHESIS: The proinflammatory cytokine TNF-alpha has been implicated in the pathogenesis of insulin resistance and type 2 diabetes, and variation in the gene encoding TNF-alpha (TNF) has shown inconsistent associations with susceptibility to both conditions. Additionally, the coding non-synon...

Полное описание

Библиографические подробности
Главные авторы:	Zeggini, E, Groves, C, Parkinson, JR, Halford, S, Owen, K, Frayling, T, Walker, M, Hitman, G, Levy, J, O'Rahilly, S, Hattersley, A, McCarthy, M
Формат:	Journal article
Язык:	English
Опубликовано:	2005

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