Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.

Large-scale studies of the association between variation at the TNF/LTA locus and susceptibility to type 2 diabetes.

AIMS/HYPOTHESIS: The proinflammatory cytokine TNF-alpha has been implicated in the pathogenesis of insulin resistance and type 2 diabetes, and variation in the gene encoding TNF-alpha (TNF) has shown inconsistent associations with susceptibility to both conditions. Additionally, the coding non-synon...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Zeggini, E, Groves, C, Parkinson, JR, Halford, S, Owen, K, Frayling, T, Walker, M, Hitman, G, Levy, J, O'Rahilly, S, Hattersley, A, McCarthy, M
التنسيق:	Journal article
اللغة:	English
منشور في:	2005

مواد مشابهة

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction.
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Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.
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