Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading

Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading

X-inactive specific transcript (Xist) RNA directs the process of X chromosome inactivation in mammals by spreading in cis along the chromosome from which it is transcribed and recruiting chromatin modifiers to silence gene transcription. To elucidate mechanisms of Xist RNA cis-confinement, we establ...

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Bibliographische Detailangaben
Hauptverfasser:	Rodermund, L, Coker, H, Oldenkamp, R, Wei, G, Bowness, J, Rajkumar, B, Nesterova, T, Susano Pinto, DM, Schermelleh, L, Brockdorff, N
Format:	Journal article
Sprache:	English
Veröffentlicht:	American Association for the Advancement of Science 2021

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