Oxidation of p-aminophenols and formal radical cyclization onto benzene rings: formation of benzo-fused nitrogen heterocycles.

p-Iodophenol and its O-MOM-protected ether can be converted into iodoamines 2. These give cross-conjugated ketones 3 on oxidation with hypervalent iodides in the presence of methanol, and the ketones undergo radical cyclization. Exposure of the products to acid or sequential treatment with a Grignar...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Fletcher, S, Clive, D, Peng, J, Wingert, D
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2005