SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops
A recent Nature paper by Xu et al describes an important link between RNA polymerase II promoterproximal pausing and genome stability maintenance orchestrated by liquid droplet formation to reduce unwanted R-loop accumulation.
Κύριος συγγραφέας: | Gromak, N |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Cell Press
2023
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Mechanisms of SOSS‐Integrator–PP2A complex in attenuating R‐loops and promoting genome stability
ανά: Jingwen Wang, κ.ά.
Έκδοση: (2024-01-01) -
Senataxin: genome guardian at the interface of transcription and neurodegeneration
ανά: Groh, M, κ.ά.
Έκδοση: (2016) -
R-loop immunoprecipitation: a method to detect R-loop interacting factors
ανά: Beghè, C, κ.ά.
Έκδοση: (2022) -
An implementation of LoSS detection using SOSS model
ανά: Rohani, M.F, κ.ά.
Έκδοση: (2007) -
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
ανά: Ma, TS, κ.ά.
Έκδοση: (2023)