SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops

A recent Nature paper by Xu et al describes an important link between RNA polymerase II promoterproximal pausing and genome stability maintenance orchestrated by liquid droplet formation to reduce unwanted R-loop accumulation.

Bibliográfalaš dieđut
Váldodahkki:	Gromak, N
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	Cell Press 2023

Geahča maid

Mechanisms of SOSS‐Integrator–PP2A complex in attenuating R‐loops and promoting genome stability
Dahkki: Jingwen Wang, et al.
Almmustuhtton: (2024-01-01)

Senataxin: genome guardian at the interface of transcription and neurodegeneration
Dahkki: Groh, M, et al.
Almmustuhtton: (2016)

R-loop immunoprecipitation: a method to detect R-loop interacting factors
Dahkki: Beghè, C, et al.
Almmustuhtton: (2022)

An implementation of LoSS detection using SOSS model
Dahkki: Rohani, M.F, et al.
Almmustuhtton: (2007)

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
Dahkki: Ma, TS, et al.
Almmustuhtton: (2023)

Out of balance: R-loops in human disease
Dahkki: Groh, M, et al.
Almmustuhtton: (2014)

PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Dahkki: Sundarraj Jayakumar, et al.
Almmustuhtton: (2024-01-01)

R-loops promote antisense transcription across the mammalian genome
Dahkki: Tan-Wong, SM, et al.
Almmustuhtton: (2019)

Evaluation of dynamic corneal response parameters and the biomechanical E-staging after Intacs® SK implantation in keratoconus
Dahkki: Elias Flockerzi, et al.
Almmustuhtton: (2024-04-01)

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
Dahkki: McCann, JL, et al.
Almmustuhtton: (2023)

RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage
Dahkki: Cristini, A, et al.
Almmustuhtton: (2018)

Metabolic gatekeeper function of B-lymphoid transcription factors
Dahkki: Chan, LN, et al.
Almmustuhtton: (2017)

Author Correction: PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
Dahkki: Sundarraj Jayakumar, et al.
Almmustuhtton: (2024-06-01)

A new gatekeeper to control oligodendrogenesis.
Dahkki: Tim Czopka
Almmustuhtton: (2024-07-01)

Who Am I? Psychometric properties of the persian version of the sense of self scale (SOSS)
Dahkki: Golnaz Mazaheri Nejad Fard, et al.
Almmustuhtton: (2024-12-01)

Dual processing of R-loops and topoisomerase I induces transcription-dependent DNA double-strand breaks
Dahkki: Cristini, A, et al.
Almmustuhtton: (2019)

Green gatekeepers
Dahkki: Enriques, L, et al.
Almmustuhtton: (2024)

Gatekeeping Science
Dahkki: Jan Thohauge Frederiksen, et al.
Almmustuhtton: (2025-01-01)

RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
Dahkki: Cristini, A, et al.
Almmustuhtton: (2022)

Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions
Dahkki: Kiwon Park, et al.
Almmustuhtton: (2024-12-01)

RAD52 resolves transcription-replication conflicts to mitigate R-loop induced genome instability
Dahkki: Manisha Jalan, et al.
Almmustuhtton: (2024-09-01)

The influence of gatekeepers on project performance in a major R&D facility
Dahkki: Katz, Ralph., et al.
Almmustuhtton: (2009)

Edited GluR2, a gatekeeper for motor neurone survival?
Dahkki: Buckingham, S, et al.
Almmustuhtton: (2008)

Health Service Gatekeepers.
Dahkki: Malcomson, J
Almmustuhtton: (2003)

Health service gatekeepers
Dahkki: Malcomson, J
Almmustuhtton: (2003)

Health Service Gatekeepers.
Dahkki: Malcomson, J
Almmustuhtton: (2004)

Health Service Gatekeepers.
Dahkki: Malcomson, J
Almmustuhtton: (2003)

Gatekeeping at BiO
Dahkki: Daniel A. Gorelick
Almmustuhtton: (2023-12-01)

Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks
Dahkki: Long, Q, et al.
Almmustuhtton: (2024)

Who Keeps the Gate? Digital Gatekeeping in New Media
Dahkki: Karolina Pałka-Suchojad
Almmustuhtton: (2021-06-01)

Gatekeepers : the professions and corporate governance /
Dahkki: Coffee, John C., 1944-
Almmustuhtton: (2006)

On Gatekeepers and Structural Competition Problems
Dahkki: Christian Rusche, et al.
Almmustuhtton: (2021-08-01)

Os gatekeepers na engenharia
Dahkki: Jeannette M. Kremer
Almmustuhtton: (1981-06-01)

Traducción y validez de la Stigma of Suicide Scale Short Form (SOSS-SF) en población peruana
Dahkki: Jonatan Baños-Chaparro, et al.
Almmustuhtton: (2023-05-01)

R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus.
Dahkki: Sun, Q, et al.
Almmustuhtton: (2013)

Gatekeeping girls’ access to education: an exploration of matrilineal relationships, gatekeepers, and contentions at the micro-household-level
Dahkki: Akuffo, AG
Almmustuhtton: (2024)

Post-publication gatekeeping practices: Exploring conversational and visual gatekeeping on Finnish newspapers’ Instagram accounts
Dahkki: Salonen Margareta, et al.
Almmustuhtton: (2023-09-01)

JWST-TST DREAMS: A Supersolar Metallicity in WASP-17 b’s Dayside Atmosphere from NIRISS SOSS Eclipse Spectroscopy
Dahkki: Amélie Gressier, et al.
Almmustuhtton: (2025-01-01)

R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome
Dahkki: Groh, M, et al.
Almmustuhtton: (2014)

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.
Dahkki: West, S, et al.
Almmustuhtton: (2004)