High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam.
We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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Cambridge University Press
2015
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| _version_ | 1826293287446642688 |
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| author | Tu, L Hoang, N Cuong, N Campbell, J Bryant, J Hoa, N Kiet, B Thompson, C Duy, D Phat, V Hien, V Thwaites, G Baker, S Carrique-Mas, J |
| author_facet | Tu, L Hoang, N Cuong, N Campbell, J Bryant, J Hoa, N Kiet, B Thompson, C Duy, D Phat, V Hien, V Thwaites, G Baker, S Carrique-Mas, J |
| author_sort | Tu, L |
| collection | OXFORD |
| description | We investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64·7%, 94·3% and 91·3% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77·6%) against tetracycline, moderate resistance (20-30%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance (<5%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control. |
| first_indexed | 2024-03-07T03:27:47Z |
| format | Journal article |
| id | oxford-uuid:b9a80093-92e8-49ac-9be4-01221c2c0d3d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:27:47Z |
| publishDate | 2015 |
| publisher | Cambridge University Press |
| record_format | dspace |
| spelling | oxford-uuid:b9a80093-92e8-49ac-9be4-01221c2c0d3d2022-03-27T05:04:24ZHigh levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b9a80093-92e8-49ac-9be4-01221c2c0d3dEnglishSymplectic Elements at OxfordCambridge University Press2015Tu, LHoang, NCuong, NCampbell, JBryant, JHoa, NKiet, BThompson, CDuy, DPhat, VHien, VThwaites, GBaker, SCarrique-Mas, JWe investigated the prevalence, diversity, and antimicrobial resistance (AMR) profiles of non-typhoidal Salmonella (NTS) and associated risk factors on 341 pig, chicken, and duck farms in Dong Thap province (Mekong Delta, Vietnam). Sampling was stratified by species, district (four categories), and farm size (three categories). Pooled faeces, collected using boot swabs, were tested using ISO 6575: 2002 (Annex D). Isolates were serogrouped; group B isolates were tested by polymerase chain reaction to detect S. Typhimurium and (monophasic) serovar 4,[5],12:i:- variants. The farm-level adjusted NTS prevalence was 64·7%, 94·3% and 91·3% for chicken, duck and pig farms, respectively. Factors independently associated with NTS were duck farms [odds ratio (OR) 21·2], farm with >50 pigs (OR 11·9), pig farm with 5-50 pigs (OR 4·88) (vs. chickens), and frequent rodent sightings (OR 2·3). Both S. Typhimurium and monophasic S. Typhimurium were more common in duck farms. Isolates had a high prevalence of resistance (77·6%) against tetracycline, moderate resistance (20-30%) against chloramphenicol, sulfamethoxazole-trimethoprim, ampicillin and nalidixic acid, and low resistance (<5%) against ciprofloxacin and third-generation cephalosporins. Multidrug resistance (resistance against ⩾3 classes of antimicrobial) was independently associated with monophasic S. Typhimurium and other group B isolates (excluding S. Typhimurium) and pig farms. The unusually high prevalence of NTS on Mekong Delta farms poses formidable challenges for control. |
| spellingShingle | Tu, L Hoang, N Cuong, N Campbell, J Bryant, J Hoa, N Kiet, B Thompson, C Duy, D Phat, V Hien, V Thwaites, G Baker, S Carrique-Mas, J High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title | High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title_full | High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title_fullStr | High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title_full_unstemmed | High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title_short | High levels of contamination and antimicrobial-resistant non-typhoidal Salmonella serovars on pig and poultry farms in the Mekong Delta of Vietnam. |
| title_sort | high levels of contamination and antimicrobial resistant non typhoidal salmonella serovars on pig and poultry farms in the mekong delta of vietnam |
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