Partial reduction of pyrroles: application to natural product synthesis.

Partial reduction of pyrroles: application to natural product synthesis.

The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstituted pyrrolines in good yields and with excellent diastereoselectivities. A novel methodology has been developed to carry out reductive aldol reactions on 2-substituted N-Boc pyrroles; use of aldehyde...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Donohoe, T, Thomas, R
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2007

Eitemau Tebyg

Flexibility in the partial reduction of 2,5-disubstituted pyrroles: application to the synthesis of DMDP.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2003)

Knorr-Rabe partial reduction of pyrroles: Application to the synthesis of indolizidine alkaloids
gan: Brendon S. Gourlay, et al.
Cyhoeddwyd: (2008-01-01)

Stereoselective reductive alkylation of 2,5-disubstituted pyrroles: a role for naphthalene in the partial reduction of heterocycles
gan: Donohoe, T, et al.
Cyhoeddwyd: (2000)

The stereoselective birch reduction of pyrroles
gan: Donohoe, T, et al.
Cyhoeddwyd: (1999)

Birch Reduction of Electron-Deficient Pyrroles.
gan: Donohoe, T, et al.
Cyhoeddwyd: (1996)

The partial reduction of electron-deficient pyrroles: procedures describing both Birch (Li/NH3) and ammonia-free (Li/DBB) conditions.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2007)

Stereoselectivity in the double reductive alkylation of pyrroles: synthesis of cis-3,4-disubstituted pyrrolidines
gan: Donohoe, T, et al.
Cyhoeddwyd: (1999)

The birch reduction of 3-substituted pyrroles
gan: Donohoe, T, et al.
Cyhoeddwyd: (1998)

Enantioselective partial reduction of 2,5-disubstituted pyrroles via a chiral protonation approach.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2004)

The birch reduction of 3-substituted and 3,4-disubstituted pyrroles.
gan: Harji, R, et al.
Cyhoeddwyd: (1999)

Diastereoselective reductive aldol reactions of Boc-protected electron deficient pyrroles
gan: Donohoe, T, et al.
Cyhoeddwyd: (2003)

Reduction of electron-deficient pyrroles using group I and II metals in ammonia
gan: Donohoe, T, et al.
Cyhoeddwyd: (1998)

Photochemical alkene isomerization for the synthesis of polysubstituted furans and pyrroles under neutral conditions
gan: Walker, J, et al.
Cyhoeddwyd: (2019)

Recent progress in the total synthesis of pyrrole-containing natural products (2011-2020)
gan: Singh, N, et al.
Cyhoeddwyd: (2021)

Rearrangement of pyrrolines derived from the Birch reduction of electron-deficient pyrroles: Radical ring-expansion to substituted tetrahydropyridines
gan: Turner, P, et al.
Cyhoeddwyd: (2004)

Rearrangement of pyrrolines derived from the Birch reduction of electron-deficient pyrroles: radical ring-expansion to substituted tetrahydropyridines.
gan: Turner, P, et al.
Cyhoeddwyd: (2004)

The partial reduction of heterocycles: an alternative to the Birch reduction
gan: Donohoe, T, et al.
Cyhoeddwyd: (2000)

Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents
gan: Rania Helmy Abd El-Hameed, et al.
Cyhoeddwyd: (2021-01-01)

Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20s proteasome inhibitor, clasto-lactacystin beta-lactone.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2005)

ORGN 873-Investigations into the partial reduction of substituted pyridines and its application towards the total synthesis of cylindricine A
gan: Johnson, D, et al.
Cyhoeddwyd: (2006)

Natural Hydroxyapatite: Green Catalyst for the Synthesis of Pyrroles, Inhibitors of Corrosion
gan: Abdelhadi Louroubi, et al.
Cyhoeddwyd: (2021-01-01)

Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks
gan: Andrej Emanuel Cotman, et al.
Cyhoeddwyd: (2021-03-01)

Substituted pyrroles via olefin cross-metathesis.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2010)

Recent advances in the synthesis of pyrroles
gan: Iqbal, S, et al.
Cyhoeddwyd: (2020)

Application of catalytic Z-selective olefin metathesis in natural product synthesis
gan: Werrel, S, et al.
Cyhoeddwyd: (2015)

Synthesis of meso-pyrrole-substituted corroles by condensation of 1,9-diformyldipyrromethanes with pyrrole
gan: Baris Temelli, et al.
Cyhoeddwyd: (2022-10-01)

Highlights of natural product synthesis
gan: Donohoe, T, et al.
Cyhoeddwyd: (2006)

Investigations into the partial reduction of substitued pyridines
gan: Johnson, D, et al.
Cyhoeddwyd: (2005)

Synthesis of Pyrrole Phosphonate Esters: Emphasis on Pyrrole NH Acids and Dialkylacetylenic Esters Substitution
gan: Malek Taher Maghsoodlou, et al.
Cyhoeddwyd: (2008-03-01)

Metal-mediated synthesis of furans and pyrroles
gan: Nitin T. Patil, et al.
Cyhoeddwyd: (2007-02-01)

Synthesis and bioactivity of pyrrole-conjugated phosphopeptides
gan: Qiuxin Zhang, et al.
Cyhoeddwyd: (2022-01-01)

An efficient copper-catalysed pyrrole synthesis
gan: Damian G. Dunford, et al.
Cyhoeddwyd: (2012-09-01)

Partial reduction of electron-deficient pyridines
gan: Donohoe, T, et al.
Cyhoeddwyd: (2000)

ORGN 558-Formation of enantiopure pyrroline building blocks for natural product synthesis
gan: Thomas, R, et al.
Cyhoeddwyd: (2006)

Enantiopure oxazolidinones as chiral acids in the asymmetric protonation of N-Boc pyrrole derived enolates.
gan: Carbery, DR, et al.
Cyhoeddwyd: (2004)

Technology for the production of disubstituted pyrroles
gan: Safarov Megli Djumayevich
Cyhoeddwyd: (2023-01-01)

An Efficient Synthesis of Aryl-Substituted Pyrroles by the Suzuki–Miyaura Coupling Reaction of SEM-Protected Pyrroles
gan: Keli Cui, et al.
Cyhoeddwyd: (2019-04-01)

Facile synthesis of 2-alkyl/aryloxy-2H-azirines and their application in the synthesis of pyrroles
gan: Qi, Xinxin, et al.
Cyhoeddwyd: (2013)

Natural product synthesis as a challenging test of newly developed methodology.
gan: Donohoe, T, et al.
Cyhoeddwyd: (2012)

Oxidative cyclization for the synthesis of complex tetrahydrofuran-containing natural products
gan: Pullin, R, et al.
Cyhoeddwyd: (2013)