Partial reduction of pyrroles: application to natural product synthesis.

The partial reduction of N-Boc pyrroles has been explored giving stereoselective routes to disubstituted pyrrolines in good yields and with excellent diastereoselectivities. A novel methodology has been developed to carry out reductive aldol reactions on 2-substituted N-Boc pyrroles; use of aldehyde...

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Autori principali: Donohoe, T, Thomas, R
Natura: Journal article
Lingua:English
Pubblicazione: 2007