Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial

<strong>Purpose:</strong> Medication adherence (MA) is a key factor for hypertensive patients’ blood pressure control and forgetfulness is one of the main reasons that cause medication non-adherence. If effective, low-cost reminder package (LCRP) has great potentials for large-scale prom...

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Main Authors: Shen, Y, Wang, T, Gao, M, Zhu, X, Zhang, X, He, C, Li, Y, Sun, X
Format: Journal article
Language:English
Published: Dove Medical Press 2019
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author Shen, Y
Wang, T
Gao, M
Zhu, X
Zhang, X
He, C
Li, Y
Sun, X
author_facet Shen, Y
Wang, T
Gao, M
Zhu, X
Zhang, X
He, C
Li, Y
Sun, X
author_sort Shen, Y
collection OXFORD
description <strong>Purpose:</strong> Medication adherence (MA) is a key factor for hypertensive patients’ blood pressure control and forgetfulness is one of the main reasons that cause medication non-adherence. If effective, low-cost reminder package (LCRP) has great potentials for large-scale promotion. Therefore, this study aims to evaluate the effectiveness of combining LCRP and health education to improve MA among hypertensive patients. <br> <strong>Patients and methods:</strong> A clustered randomized controlled trial was performed in Beijing. A total of 518 hypertensive patients recruited from 8 community health care centers were randomized to receive LCRP combined with case-based health education or usual care. Randomization was performed at community level. Multilevel modeling was used to evaluate the study effect. <br> <strong>Results:</strong> MA scores did not differ significantly at baseline between the intervention group and the control group. The results of multilevel modeling indicated that MA scores increased more in the intervention group, and the intervention effect on MA was 0.287 (95% CI: [0.103, 0.471], P=0.002). Patients’ systolic blood pressure (SBP) and diastolic blood pressure (DBP) were not improved (SBP: difference=0.536, 95% CI [−3.207, 4.278]; DBP: difference=−0.927, 95% CI [−3.283, 1.428]). <br> <strong>Conclusion:</strong> LCRP combined with case-based health education could significantly improve hypertensive patients’ MA.
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spelling oxford-uuid:b9b4bc3a-f11f-44c6-a08b-c8449ca2cb332022-03-27T05:04:51ZEffectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trialJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b9b4bc3a-f11f-44c6-a08b-c8449ca2cb33EnglishSymplectic ElementsDove Medical Press2019Shen, YWang, TGao, MZhu, XZhang, XHe, CLi, YSun, X<strong>Purpose:</strong> Medication adherence (MA) is a key factor for hypertensive patients’ blood pressure control and forgetfulness is one of the main reasons that cause medication non-adherence. If effective, low-cost reminder package (LCRP) has great potentials for large-scale promotion. Therefore, this study aims to evaluate the effectiveness of combining LCRP and health education to improve MA among hypertensive patients. <br> <strong>Patients and methods:</strong> A clustered randomized controlled trial was performed in Beijing. A total of 518 hypertensive patients recruited from 8 community health care centers were randomized to receive LCRP combined with case-based health education or usual care. Randomization was performed at community level. Multilevel modeling was used to evaluate the study effect. <br> <strong>Results:</strong> MA scores did not differ significantly at baseline between the intervention group and the control group. The results of multilevel modeling indicated that MA scores increased more in the intervention group, and the intervention effect on MA was 0.287 (95% CI: [0.103, 0.471], P=0.002). Patients’ systolic blood pressure (SBP) and diastolic blood pressure (DBP) were not improved (SBP: difference=0.536, 95% CI [−3.207, 4.278]; DBP: difference=−0.927, 95% CI [−3.283, 1.428]). <br> <strong>Conclusion:</strong> LCRP combined with case-based health education could significantly improve hypertensive patients’ MA.
spellingShingle Shen, Y
Wang, T
Gao, M
Zhu, X
Zhang, X
He, C
Li, Y
Sun, X
Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title_full Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title_fullStr Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title_full_unstemmed Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title_short Effectiveness of low-cost reminder package combined with case-based health education to improve hypertensive patients’ medication adherence: a clustered randomized controlled trial
title_sort effectiveness of low cost reminder package combined with case based health education to improve hypertensive patients medication adherence a clustered randomized controlled trial
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