GPRC5B a putative glutamate-receptor candidate is negative modulator of insulin secretion.

GPRC5B is an orphan receptor belonging to the group C family of G protein-coupled receptors (GPCRs). GPRC5B is abundantly expressed in both human and mouse pancreatic islets, and both GPRC5B mRNA and protein are up-regulated 2.5-fold in islets from organ donors with type 2 diabetes. Expression of Gp...

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Bibliographic Details
Main Authors: Soni, A, Amisten, S, Rorsman, P, Salehi, A
Format: Journal article
Language:English
Published: 2013