In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.

In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange.

Rapid binding of peptides to MHC class II molecules is normally limited to a deep endosomal compartment where the coordinate action of low pH and HLA-DM displaces the invariant chain remnant CLIP or other peptides from the binding site. Exogenously added peptides are subject to proteolytic degradati...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Call, M, Xing, X, Cuny, G, Seth, N, Altmann, D, Fugger, L, Krogsgaard, M, Stein, R, Wucherpfennig, K
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2009

Ижил төстэй зүйлс

Rapid peptide exchange on MHC class I by small molecules elucidates dynamics of bound peptide
-н: Andries Hadeler, зэрэг
Хэвлэсэн: (2022-01-01)

Peptide Loading on MHC Class I Molecules of Tumor Cells
-н: Loredana Cifaldi, зэрэг
Хэвлэсэн: (2016-09-01)

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
-н: Shashank Gupta, зэрэг
Хэвлэсэн: (2008-01-01)

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst
-н: Clemens Hermann, зэрэг
Хэвлэсэн: (2015-10-01)

Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules.
-н: Dzhambazov, B, зэрэг
Хэвлэсэн: (2006)

Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection
-н: Raghavendra Anjanappa, зэрэг
Хэвлэсэн: (2020-03-01)

Limitations of Ab initio predictions of peptide binding to MHC class II molecules.
-н: Hao Zhang, зэрэг
Хэвлэсэн: (2010-02-01)

Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules
-н: Yingze Zhao, зэрэг
Хэвлэсэн: (2022-04-01)

Biophysical evidence for conformational change in MHC class I molecules upon peptide binding
-н: Springer, S, зэрэг
Хэвлэсэн: (1997)

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding
-н: Paul E Chappell, зэрэг
Хэвлэсэн: (2015-04-01)

Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms
-н: Feng Lin, зэрэг
Хэвлэсэн: (2007-11-01)

Distinct peptide loading pathways for MHC class II molecules associated with alternative Ii chain isoforms.
-н: Bikoff, E, зэрэг
Хэвлэсэн: (1998)

A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity.
-н: Elvin, J, зэрэг
Хэвлэсэн: (1993)

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer.
-н: Spies, T, зэрэг
Хэвлэсэн: (1992)

Structures of an MHC class I molecule from B21 chickens illustrate promiscuous peptide binding.
-н: Koch, M, зэрэг
Хэвлэсэн: (2007)

A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules
-н: Denise S. M. Boulanger, зэрэг
Хэвлэсэн: (2018-07-01)

Peptide binding characteristics of the non-classical class Ib MHC molecule HLA-E assessed by a recombinant random peptide approach
-н: Joly Etienne, зэрэг
Хэвлэсэн: (2001-06-01)

A community resource benchmarking predictions of peptide binding to MHC-I molecules.
-н: Bjoern Peters, зэрэг
Хэвлэсэн: (2006-06-01)

Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules
-н: Spencer, CT, зэрэг
Хэвлэсэн: (2015)

The Discovery of Small-Molecule Mimicking Peptides through Phage Display
-н: Brendan P. Orner, зэрэг
Хэвлэсэн: (2011-01-01)

Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens.
-н: Bikoff, E
Хэвлэсэн: (1992)

MHC II molecules in inflammatory diseases: interplay of qualities and quantities.
-н: Friese, M, зэрэг
Хэвлэсэн: (2005)

Functions of nonclassical MHC and non-MHC-encoded class I molecules.
-н: Braud, V, зэрэг
Хэвлэсэн: (1999)

Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response
-н: Arpita Balakrishnan, зэрэг
Хэвлэсэн: (2025-01-01)

Degenerate T-cell recognition of peptides on MHC molecules creates large holes in the T-cell repertoire.
-н: Jorg J A Calis, зэрэг
Хэвлэсэн: (2012-01-01)

TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap
-н: Andrew C. McShan, зэрэг
Хэвлэсэн: (2021-05-01)

MHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology and Medicine.
-н: Bowness, P, зэрэг
Хэвлэсэн: (2009)

Determination of class II peptide-MHC repertoires and recognition via large yeast-displayed libraries
-н: Rappazzo, Charles Garrett.
Хэвлэсэн: (2020)

T Cells Engaging the Conserved MHC Class Ib Molecule Qa-1b with TAP-Independent Peptides Are Semi-Invariant Lymphocytes
-н: Elien M. Doorduijn, зэрэг
Хэвлэсэн: (2018-01-01)

Yeast Display for the Identification of Peptide-MHC Ligands of Immune Receptors
-н: Huisman, Brooke D, зэрэг
Хэвлэсэн: (2023)

Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
-н: O'Callaghan, C, зэрэг
Хэвлэсэн: (1998)

Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules
-н: Georgia F. Papadaki, зэрэг
Хэвлэсэн: (2023-01-01)

Assembly of MHC class I molecules analyzed in vitro.
-н: Townsend, A, зэрэг
Хэвлэсэн: (1990)

MHC class II complexes sample intermediate states along the peptide exchange pathway
-н: Marek Wieczorek, зэрэг
Хэвлэсэн: (2016-11-01)

Fast association rates suggest a conformational change in the MHC class I molecule H-2Db upon peptide binding.
-н: Springer, S, зэрэг
Хэвлэсэн: (1998)

A Peptide Filtering Relation Quantifies MHC Class I Peptide Optimization
-н: Dalchau, N, зэрэг
Хэвлэсэн: (2011)

A peptide filtering relation quantifies MHC class I peptide optimization
-н: Dalchau, N, зэрэг
Хэвлэсэн: (2011)

A peptide filtering relation quantifies MHC class I peptide optimization.
-н: Dalchau, N, зэрэг
Хэвлэсэн: (2011)

A peptide filtering relation quantifies MHC class I peptide optimization.
-н: Neil Dalchau, зэрэг
Хэвлэсэн: (2011-10-01)

Evidence of widespread binding of HLA class I molecules to peptides.
-н: Frelinger, J, зэрэг
Хэвлэсэн: (1990)