Association between single-nucleotide polymorphisms in Mal/TIRAP and interleukin-10 genes and susceptibility to invasive haemophilus influenzae serotype b infection in immunized children.

BACKGROUND: The development of invasive Haemophilus influenzae serotype b (Hib) disease after prior immunization with the Hib conjugate vaccine (ie, Hib vaccine failure) is extremely rare, suggesting that affected children may have an underlying genetic susceptibility in their immune response. The...

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Bibliographic Details
Main Authors: Ladhani, SN, Davila, S, Hibberd, M, Heath, P, Ramsay, M, Slack, M, Pollard, A, Booy, R
Format: Journal article
Language:English
Published: 2010