Low-speed centrifugation of retroviral vectors absorbed to a particulate substrate: a highly effective means of enhancing retroviral titre.

For many gene therapy applications the effective titre of retroviral vectors is a limiting factor both in vitro and in vivo. Purification and concentration of retrovirus from packaging cell supernatant can overcome this problem. To this end we have investigated a novel procedure which involves compl...

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書目詳細資料
Main Authors: Darling, D, Hughes, C, Galea-Lauri, J, Gäken, J, Trayner, I, Kuiper, M, Farzaneh, F
格式: Journal article
語言:English
出版: 2000