Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm
<jats:p>Recombination is critical to meiosis and evolution, yet many aspects of the physical exchange of DNA via crossovers remain poorly understood. We report an approach for single-cell whole-genome DNA sequencing by which we sequenced 217 individual hybrid mouse sperm, providing a kilobase-...
Hlavní autoři: | , , , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
American Association for the Advancement of Science
2019
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