Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM

Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM

Glioblastoma multiforme (GBM) remains a cancer with a poor prognosis and few effective therapeutic options. Successful medical management of GBM is limited by the restricted access of drugs to the central nervous system (CNS) caused by the blood brain barrier (BBB). We previously showed that a subse...

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Hlavní autoři: Przystal, J, Hajji, N, Khozoie, C, Renziehausen, A, Zeng, Q, Abaitua, F, Hajitou, A, Suwan, K, Want, E, Bomalaski, J, Szlosarek, P, O'Neill, K, Crook, T, Syed, N
Médium: Journal article
Jazyk:English
Vydáno: Nature Publishing Group 2018
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