Three cases of androgen-dependent disease associated with myotonic dystrophy.

Three cases of androgen-dependent disease in females with myotonic dystrophy are described. Serum androgens in individuals affected by myotonic dystrophy are known to be lower on average than in normal controls. Despite this these three females developed diseases that are androgen dependent, includi...

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Chi tiết về thư mục
Những tác giả chính: Cooper, S, Dawber, R, Hilton-Jones, D
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2003
Miêu tả
Tóm tắt:Three cases of androgen-dependent disease in females with myotonic dystrophy are described. Serum androgens in individuals affected by myotonic dystrophy are known to be lower on average than in normal controls. Despite this these three females developed diseases that are androgen dependent, including acne, hidradenitis suppurativa, androgenetic alopecia and keratosis pilaris. These cases support the hypothesis that the peripheral response to androgens rather than absolute circulating levels of androgens is important in androgen-dependent conditions.