A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains.

A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains.

Catechol-O-methyltransferase (COMT) is a key enzyme for dopamine catabolism and COMT is a candidate gene for human psychiatric disorders. In mouse it is located on chromosome 16 in a large genomic region of extremely low variation among the classical inbred strains, with no confirmed single nucleoti...

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Bibliografische gegevens
Hoofdauteurs:	Kember, R, Fernandes, C, Tunbridge, E, Liu, L, Payá-Cano, J, Parsons, M, Schalkwyk, L
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2010

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