Recovery from emotion recognition impairment after temporal lobectomy.
Mesial temporal lobe epilepsy (MTLE) can be associated with emotion recognition impairment that can be particularly severe in patients with early onset seizures (1-3). Whereas, there is growing evidence that memory and language can improve in seizure-free patients after anterior temporal lobectomy (...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers Research Foundation
2014
|
| _version_ | 1826293377050607616 |
|---|---|
| author | Benuzzi, F Zamboni, G Meletti, S Serafini, M Lui, F Baraldi, P Duzzi, D Rubboli, G Tassinari, C Nichelli, P |
| author_facet | Benuzzi, F Zamboni, G Meletti, S Serafini, M Lui, F Baraldi, P Duzzi, D Rubboli, G Tassinari, C Nichelli, P |
| author_sort | Benuzzi, F |
| collection | OXFORD |
| description | Mesial temporal lobe epilepsy (MTLE) can be associated with emotion recognition impairment that can be particularly severe in patients with early onset seizures (1-3). Whereas, there is growing evidence that memory and language can improve in seizure-free patients after anterior temporal lobectomy (ATL) (4), the effects of surgery on emotional processing are still unknown. We used functional magnetic resonance imaging (fMRI) to investigate short-term reorganization of networks engaged in facial emotion recognition in MTLE patients. Behavioral and fMRI data were collected from six patients before and after ATL. During the fMRI scan, patients were asked to make a gender decision on fearful and neutral faces. Behavioral data demonstrated that two patients with early onset right MTLE were impaired in fear recognition while fMRI results showed they lacked specific activations for fearful faces. Post-ATL behavioral data showed improved emotion recognition ability, while fMRI demonstrated the recruitment of a functional network for fearful face processing. Our results suggest that ATL elicited brain plasticity mechanisms allowing behavioral and fMRI improvement in emotion recognition. |
| first_indexed | 2024-03-07T03:29:09Z |
| format | Journal article |
| id | oxford-uuid:ba16e917-801d-4daa-ae34-95529a991e02 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:29:09Z |
| publishDate | 2014 |
| publisher | Frontiers Research Foundation |
| record_format | dspace |
| spelling | oxford-uuid:ba16e917-801d-4daa-ae34-95529a991e022022-03-27T05:07:33ZRecovery from emotion recognition impairment after temporal lobectomy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ba16e917-801d-4daa-ae34-95529a991e02EnglishSymplectic Elements at OxfordFrontiers Research Foundation2014Benuzzi, FZamboni, GMeletti, SSerafini, MLui, FBaraldi, PDuzzi, DRubboli, GTassinari, CNichelli, PMesial temporal lobe epilepsy (MTLE) can be associated with emotion recognition impairment that can be particularly severe in patients with early onset seizures (1-3). Whereas, there is growing evidence that memory and language can improve in seizure-free patients after anterior temporal lobectomy (ATL) (4), the effects of surgery on emotional processing are still unknown. We used functional magnetic resonance imaging (fMRI) to investigate short-term reorganization of networks engaged in facial emotion recognition in MTLE patients. Behavioral and fMRI data were collected from six patients before and after ATL. During the fMRI scan, patients were asked to make a gender decision on fearful and neutral faces. Behavioral data demonstrated that two patients with early onset right MTLE were impaired in fear recognition while fMRI results showed they lacked specific activations for fearful faces. Post-ATL behavioral data showed improved emotion recognition ability, while fMRI demonstrated the recruitment of a functional network for fearful face processing. Our results suggest that ATL elicited brain plasticity mechanisms allowing behavioral and fMRI improvement in emotion recognition. |
| spellingShingle | Benuzzi, F Zamboni, G Meletti, S Serafini, M Lui, F Baraldi, P Duzzi, D Rubboli, G Tassinari, C Nichelli, P Recovery from emotion recognition impairment after temporal lobectomy. |
| title | Recovery from emotion recognition impairment after temporal lobectomy. |
| title_full | Recovery from emotion recognition impairment after temporal lobectomy. |
| title_fullStr | Recovery from emotion recognition impairment after temporal lobectomy. |
| title_full_unstemmed | Recovery from emotion recognition impairment after temporal lobectomy. |
| title_short | Recovery from emotion recognition impairment after temporal lobectomy. |
| title_sort | recovery from emotion recognition impairment after temporal lobectomy |
| work_keys_str_mv | AT benuzzif recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT zambonig recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT melettis recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT serafinim recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT luif recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT baraldip recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT duzzid recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT rubbolig recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT tassinaric recoveryfromemotionrecognitionimpairmentaftertemporallobectomy AT nichellip recoveryfromemotionrecognitionimpairmentaftertemporallobectomy |